The state of California currently has 137 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Los Angeles, San Francisco, San Diego and Sacramento.
National Program to Overcome Pelvic Pain studY (POPPY)
Recruiting
A randomized, parallel-group, investigator-blinded, comparative effectiveness trial of a fully remote, videoconference-based pelvic floor yoga program versus a physical conditioning program for women with chronic pelvic pain syndrome.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/15/2025
Locations: University of California San Francisco, San Francisco, California
Conditions: Chronic Pelvic Pain Syndrome (CPPS), Chronic Pelvic Pain Syndrome, Chronic Pelvic Pain
RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
Recruiting
To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use - and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/10/2025
Locations: Comprehensive Pain Management Center, Campbell, California +5 locations
Conditions: Pain
Patient Retrospective Outcomes (PRO)
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2025
Locations: Kern Neuroscience Institute, Bakersfield, California +9 locations
Conditions: Chronic Pain
Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS
Recruiting
This is a Phase 2, prospective, randomized, double-blind, placebo-controlled, multi-center, single-dose, pharmacodynamic study designed to evaluate the efficacy and safety of the combination product (VNX001) versus placebo and its individual components (heparin sodium and lidocaine hydrochloride (HCl)) for the reduction of bladder pain in patients with interstitial cystitis (IC) / bladder pain syndrome (BPS), Who Have an Episode of Acute Bladder Pain of Moderate to Severe Intensity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2025
Locations: IC Study LLC, Escondido, California +4 locations
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy
Recruiting
The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine (SUZ) in participants with pain associated with diabetic peripheral neuropathy (DPN).
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/09/2025
Locations: Neuro-Pain Medical Center, Fresno, California +7 locations
Conditions: Diabetic Peripheral Neuropathic Pain
Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.
Recruiting
This study is a double-blind, randomized, prospective, placebo-controlled single-center clinical research study in which 600 mg of gabapentin or placebo will be administered 2 hours preoperatively to 49 patients each undergoing wisdom teeth extraction. We will measure intraoperative opioid use, severity of pain, the number of analgesics taken, and side effect profiles (e.g. nausea/vomiting, dizziness) at the following intervals, 4 hour, 8 hour, 12 hour, 24, and 72 hour post-procedure.
Gender:
ALL
Ages:
Between 18 years and 59 years
Trial Updated:
04/03/2025
Locations: Loma Linda University Health, Loma Linda, California
Conditions: Dental Pain and Sensation Disorder, Pain, Postoperative
EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISA
Recruiting
The purpose of this study is to investigate the safety and efficacy of the current hard gelatin capsule formulation of NRD135S.E1 80 mg once daily in the treatment of PDPN when administered for 13 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/02/2025
Locations: University of California, San Diego, San Diego, California
Conditions: Painful Diabetic Neuropathy
A DirEct to PatieNt Study in Chronic Pain
Recruiting
To compile real-world, direct from patient clinical outcomes and objective metrics in patients who have received or plan to receive a commercially approved interventional medical device therapy/procedure for chronic pain in routine clinical practice.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
04/02/2025
Locations: Boston Scientific Neuromodulation, Valencia, California
Conditions: Chronic Pain
Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy
Recruiting
The purpose of this study is to evaluate the efficacy, safety, and tolerability of VX-993 in participants with pain associated with Diabetic Peripheral Neuropathy (DPN)
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/02/2025
Locations: Trovare Clinical Research, Bakersfield, California +1 locations
Conditions: Diabetic Peripheral Neuropathic Pain
Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain
Recruiting
Compile real-world outcomes of commercially approved Intracept™ Intraosseous Nerve Ablation Systems in the treatment of patients diagnosed with vertebrogenic pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/02/2025
Locations: MarinHealth Spine Institute, Larkspur, California
Conditions: Chronic Low-back Pain, Vertebrogenic Pain Syndrome
Age-dependent Effects of Smoked and Oral Delta-9-THC
Recruiting
This study will assess the age-dependent effects of smoked and oral THC on abuse liability, intoxication, analgesia and impairment as a function of age.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/01/2025
Locations: UCLA Center for Cannabis and Cannabinoids, Los Angeles, California
Conditions: Pain, Abuse, Drug, Intoxication; Cannabinoids
TAP Blocks With Ropivacaine Continuous Infusion Catheters vs Single Dose Liposomal Bupivicaine After Kidney Transplant
Recruiting
This study is a comparison of the analgesic efficacy of transversus abdominis plane (TAP) blocks with ropivacaine bolus plus continuous ropivacaine infusion via catheters versus single shot TAP blocks with liposomal bupivacaine.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: University of California Davis, Sacramento, California
Conditions: Transplant;Failure,Kidney, Pain, Postoperative